Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 339798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM339798 (US9757364, Compound 1) Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-26-14-16(13-24-26)15-8-21-20(23-12-15)4-5-22(25-21)27(6-7-28)17-9-18(29-2)11-19(10-17)30-3/h4-5,8-14,28H,6-7H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM339798 (US9757364, Compound 1) Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-26-14-16(13-24-26)15-8-21-20(23-12-15)4-5-22(25-21)27(6-7-28)17-9-18(29-2)11-19(10-17)30-3/h4-5,8-14,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM339798 (US9757364, Compound 1) Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-26-14-16(13-24-26)15-8-21-20(23-12-15)4-5-22(25-21)27(6-7-28)17-9-18(29-2)11-19(10-17)30-3/h4-5,8-14,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM339798 (US9757364, Compound 1) Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-26-14-16(13-24-26)15-8-21-20(23-12-15)4-5-22(25-21)27(6-7-28)17-9-18(29-2)11-19(10-17)30-3/h4-5,8-14,28H,6-7H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.94	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM339798 (US9757364, Compound 1) Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-26-14-16(13-24-26)15-8-21-20(23-12-15)4-5-22(25-21)27(6-7-28)17-9-18(29-2)11-19(10-17)30-3/h4-5,8-14,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair