Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 339866   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM339866 (US9757364, Compound 58) Show SMILES COc1cc(OC)c(F)c(c1)N(Cc1ncco1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C24H21FN6O3/c1-30-13-16(12-28-30)15-8-19-18(27-11-15)4-5-22(29-19)31(14-23-26-6-7-34-23)20-9-17(32-2)10-21(33-3)24(20)25/h4-13H,14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.851	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM339866 (US9757364, Compound 58) Show SMILES COc1cc(OC)c(F)c(c1)N(Cc1ncco1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C24H21FN6O3/c1-30-13-16(12-28-30)15-8-19-18(27-11-15)4-5-22(29-19)31(14-23-26-6-7-34-23)20-9-17(32-2)10-21(33-3)24(20)25/h4-13H,14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.19	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM339866 (US9757364, Compound 58) Show SMILES COc1cc(OC)c(F)c(c1)N(Cc1ncco1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C24H21FN6O3/c1-30-13-16(12-28-30)15-8-19-18(27-11-15)4-5-22(29-19)31(14-23-26-6-7-34-23)20-9-17(32-2)10-21(33-3)24(20)25/h4-13H,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.34	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM339866 (US9757364, Compound 58) Show SMILES COc1cc(OC)c(F)c(c1)N(Cc1ncco1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C24H21FN6O3/c1-30-13-16(12-28-30)15-8-19-18(27-11-15)4-5-22(29-19)31(14-23-26-6-7-34-23)20-9-17(32-2)10-21(33-3)24(20)25/h4-13H,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM339866 (US9757364, Compound 58) Show SMILES COc1cc(OC)c(F)c(c1)N(Cc1ncco1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C24H21FN6O3/c1-30-13-16(12-28-30)15-8-19-18(27-11-15)4-5-22(29-19)31(14-23-26-6-7-34-23)20-9-17(32-2)10-21(33-3)24(20)25/h4-13H,14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.9	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
					More data for this Ligand-Target Pair