Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 343157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM343157 (1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-...) Show SMILES COc1cc(c(Cl)cc1-c1[nH]c(=O)cc2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1cccc(F)c1 Show InChI InChI=1S/C25H17ClFN3O5S/c1-34-22-13-19(14-3-2-4-16(27)9-14)21(26)12-20(22)25-18-6-5-17(10-15(18)11-24(31)28-25)36(32,33)30-23-7-8-35-29-23/h2-13H,1H3,(H,28,31)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...				US Patent US9776995 (2017) BindingDB Entry DOI: 10.7270/Q2Q81G6R
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM343157 (1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-...) Show SMILES COc1cc(c(Cl)cc1-c1[nH]c(=O)cc2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1cccc(F)c1 Show InChI InChI=1S/C25H17ClFN3O5S/c1-34-22-13-19(14-3-2-4-16(27)9-14)21(26)12-20(22)25-18-6-5-17(10-15(18)11-24(31)28-25)36(32,33)30-23-7-8-35-29-23/h2-13H,1H3,(H,28,31)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay				J Med Chem 60: 5969-5989 (2017) Article DOI: 10.1021/acs.jmedchem.6b01851 BindingDB Entry DOI: 10.7270/Q2RJ4MS7
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM343157 (1-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-...) Show SMILES COc1cc(c(Cl)cc1-c1[nH]c(=O)cc2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1cccc(F)c1 Show InChI InChI=1S/C25H17ClFN3O5S/c1-34-22-13-19(14-3-2-4-16(27)9-14)21(26)12-20(22)25-18-6-5-17(10-15(18)11-24(31)28-25)36(32,33)30-23-7-8-35-29-23/h2-13H,1H3,(H,28,31)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity towards rat forebrain nicotinic acetylcholine receptor using [3H]EB as radioligand				J Med Chem 60: 5969-5989 (2017) Article DOI: 10.1021/acs.jmedchem.6b01851 BindingDB Entry DOI: 10.7270/Q2RJ4MS7
					More data for this Ligand-Target Pair