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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 350188   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-C/Cyclin-dependent kinase 8


(Homo sapiens (Human))
BDBM350188
PNG
(US10208056, Compound 20)
Show SMILES NC(=O)c1cc2c([nH]1)-c1ccncc1OC21CCOCC1
Show InChI InChI=1S/C15H15N3O3/c16-14(19)11-7-10-13(18-11)9-1-4-17-8-12(9)21-15(10)2-5-20-6-3-15/h1,4,7-8,18H,2-3,5-6H2,(H2,16,19)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 54.7n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...


US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))
BDBM350188
PNG
(US10208056, Compound 20)
Show SMILES NC(=O)c1cc2c([nH]1)-c1ccncc1OC21CCOCC1
Show InChI InChI=1S/C15H15N3O3/c16-14(19)11-7-10-13(18-11)9-1-4-17-8-12(9)21-15(10)2-5-20-6-3-15/h1,4,7-8,18H,2-3,5-6H2,(H2,16,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 206n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...


US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 19


(Homo sapiens (Human))
BDBM350188
PNG
(US10208056, Compound 20)
Show SMILES NC(=O)c1cc2c([nH]1)-c1ccncc1OC21CCOCC1
Show InChI InChI=1S/C15H15N3O3/c16-14(19)11-7-10-13(18-11)9-1-4-17-8-12(9)21-15(10)2-5-20-6-3-15/h1,4,7-8,18H,2-3,5-6H2,(H2,16,19)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 211n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...


US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair