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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 350219   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-C/Cyclin-dependent kinase 8


(Homo sapiens (Human))		BDBM350219
PNG
(US10208056, Compound 51)
Show SMILES COc1ccc(cc1)-c1c([nH]c-2c1C(C)(C)Oc1cnccc-21)C(N)=O
Show InChI InChI=1S/C20H19N3O3/c1-20(2)16-15(11-4-6-12(25-3)7-5-11)18(19(21)24)23-17(16)13-8-9-22-10-14(13)26-20/h4-10,23H,1-3H3,(H2,21,24)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 31.9n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 19


(Homo sapiens (Human))		BDBM350219
PNG
(US10208056, Compound 51)
Show SMILES COc1ccc(cc1)-c1c([nH]c-2c1C(C)(C)Oc1cnccc-21)C(N)=O
Show InChI InChI=1S/C20H19N3O3/c1-20(2)16-15(11-4-6-12(25-3)7-5-11)18(19(21)24)23-17(16)13-8-9-22-10-14(13)26-20/h4-10,23H,1-3H3,(H2,21,24)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 171n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))		BDBM350219
PNG
(US10208056, Compound 51)
Show SMILES COc1ccc(cc1)-c1c([nH]c-2c1C(C)(C)Oc1cnccc-21)C(N)=O
Show InChI InChI=1S/C20H19N3O3/c1-20(2)16-15(11-4-6-12(25-3)7-5-11)18(19(21)24)23-17(16)13-8-9-22-10-14(13)26-20/h4-10,23H,1-3H3,(H2,21,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 321n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair