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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 352025   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM352025
PNG
(US9802904, 86)
Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2cccnc2)n1
Show InChI InChI=1S/C26H26N4/c1-18(2)23-8-4-5-9-24(23)26-28-15-19(3)25(30-26)29-16-20-10-12-21(13-11-20)22-7-6-14-27-17-22/h4-15,17-18H,16H2,1-3H3,(H,28,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 61n/an/an/an/an/an/a



The United States of America, as represented by the Secretary, Department of Health and Human Services; University of Delaware

US Patent


Assay Description
This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...

US Patent US9802904 (2017)


BindingDB Entry DOI: 10.7270/Q2TF00H8
More data for this
Ligand-Target Pair
WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM352025
PNG
(US9802904, 86)
Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2cccnc2)n1
Show InChI InChI=1S/C26H26N4/c1-18(2)23-8-4-5-9-24(23)26-28-15-19(3)25(30-26)29-16-20-10-12-21(13-11-20)22-7-6-14-27-17-22/h4-15,17-18H,16H2,1-3H3,(H,28,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay

J Med Chem 57: 8099-110 (2014)


Article DOI: 10.1021/jm5010495
BindingDB Entry DOI: 10.7270/Q24X5BSH
More data for this
Ligand-Target Pair