Found 11 hits of ic50 for monomerid = 36184 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC1 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC2 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC8 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
NAD-dependent protein deacylase sirtuin-5, mitochondrial
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Technical University of Denmark
Curated by ChEMBL
| Assay Description Inhibition of SIRT5 |
J Med Chem 55: 5582-90 (2012)
Article DOI: 10.1021/jm300526r BindingDB Entry DOI: 10.7270/Q2ZS2XM7 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.62E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02067 BindingDB Entry DOI: 10.7270/Q2XD15PJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC6 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC3 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC9 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC7 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC5 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM36184
(4-phenylbutanoate)Show InChI InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC4 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |