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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 392850   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 3


(Homo sapiens (Human))		BDBM392850
PNG
(US10301306, Example 48)
Show SMILES Cc1nc(no1)-c1ccc(Cn2c3CCNC(=O)c3c(c2-c2ccncc2)-c2ccc(F)cc2)c(F)c1
Show InChI InChI=1S/C28H21F2N5O2/c1-16-33-27(34-37-16)19-2-3-20(22(30)14-19)15-35-23-10-13-32-28(36)25(23)24(17-4-6-21(29)7-5-17)26(35)18-8-11-31-12-9-18/h2-9,11-12,14H,10,13,15H2,1H3,(H,32,36)
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n/an/a<30n/an/an/an/an/an/a



GSK



Assay Description
The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...

Bioorg Med Chem Lett 18: 5018-22 (2008)


BindingDB Entry DOI: 10.7270/Q2M90C19
More data for this
Ligand-Target Pair