BindingDB PrimarySearch

Found 9 hits of ic50 for monomerid = 4703
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory concentration against human cystolic isozyme II of Carbonic anhydrase				Bioorg Med Chem Lett 14: 5703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.085 BindingDB Entry DOI: 10.7270/Q23N22VW
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory concentration against human cystolic isozyme V of Carbonic anhydrase				Bioorg Med Chem Lett 14: 5703-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.085 BindingDB Entry DOI: 10.7270/Q23N22VW
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human carbonic anhydrase 2 using 4-nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128291 BindingDB Entry DOI: 10.7270/Q2FT8QXR
TBA					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human CA2 using 4-nitrophenylacetate as substrate by esterase assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128420 BindingDB Entry DOI: 10.7270/Q2VX0MC2
TBA					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human CA9 using 4-nitrophenylacetate as substrate by esterase assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128420 BindingDB Entry DOI: 10.7270/Q2VX0MC2
TBA					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human carbonic anhydrase 9 using 4-nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128291 BindingDB Entry DOI: 10.7270/Q2FT8QXR
TBA					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human CA1 using 4-nitrophenylacetate as substrate by esterase assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128420 BindingDB Entry DOI: 10.7270/Q2VX0MC2
TBA					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human carbonic anhydrase 1 using 4-nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128291 BindingDB Entry DOI: 10.7270/Q2FT8QXR
TBA					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus (N9))	BDBM4703 (4-carboxybenzenesulfonamide 1 \| 4-sulfamoylbenzoic...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+6	n/a	n/a	n/a	n/a	6.5	37
BioCryst Pharmaceuticals, Inc.					Assay Description A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...				J Med Chem 40: 4030-52 (1997) Article DOI: 10.1021/jm970479e BindingDB Entry DOI: 10.7270/Q2X63K41
BioCryst Pharmaceuticals, Inc.					More data for this Ligand-Target Pair