Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 50002022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50002022 ((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H16N2O5/c16-11(15-20)7-10(13(19)14-8-12(17)18)6-9-4-2-1-3-5-9/h1-5,10,20H,6-8H2,(H,14,19)(H,15,16)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
UA 498 CNRS Curated by ChEMBL					Assay Description Inhibition of [3H]Ala2-Leu-enkephalin binding to Neutral endopeptidase (NEP)				J Med Chem 31: 1825-31 (1988) BindingDB Entry DOI: 10.7270/Q2R49RC8
					More data for this Ligand-Target Pair
Neprilysin (Rattus norvegicus (Rat))	BDBM50002022 ((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H16N2O5/c16-11(15-20)7-10(13(19)14-8-12(17)18)6-9-4-2-1-3-5-9/h1-5,10,20H,6-8H2,(H,14,19)(H,15,16)(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of enkephalinase purified from rat kidney.				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50002022 ((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H16N2O5/c16-11(15-20)7-10(13(19)14-8-12(17)18)6-9-4-2-1-3-5-9/h1-5,10,20H,6-8H2,(H,14,19)(H,15,16)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase activity in rabbit kidney with 20 nM [3H]-D-Ala2-Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50002022 ((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H16N2O5/c16-11(15-20)7-10(13(19)14-8-12(17)18)6-9-4-2-1-3-5-9/h1-5,10,20H,6-8H2,(H,14,19)(H,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory potency against neutral endopeptidase				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002022 ((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H16N2O5/c16-11(15-20)7-10(13(19)14-8-12(17)18)6-9-4-2-1-3-5-9/h1-5,10,20H,6-8H2,(H,14,19)(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrate				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002022 ((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C13H16N2O5/c16-11(15-20)7-10(13(19)14-8-12(17)18)6-9-4-2-1-3-5-9/h1-5,10,20H,6-8H2,(H,14,19)(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of Aminopeptidase N activity in pig kidney with 10 nM [3H]-Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair