Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Canada Curated by ChEMBL | Assay Description Inhibitory activity of the Compound was tested against HIV protease enzyme (by Dixon analysis) | J Med Chem 35: 1318-20 (1992) BindingDB Entry DOI: 10.7270/Q2W959T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured (exp 2) | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Canada Curated by ChEMBL | Assay Description Inhibitory activity of the Compound was tested against HIV protease enzyme | J Med Chem 35: 1318-20 (1992) BindingDB Entry DOI: 10.7270/Q2W959T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Canada Curated by ChEMBL | Assay Description Inhibitory activity of the Compound was tested against HIV protease enzyme | J Med Chem 35: 1318-20 (1992) BindingDB Entry DOI: 10.7270/Q2W959T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Canada Curated by ChEMBL | Assay Description Binding affinity against HIV Protease enzyme.(by Dixon analysis) | J Med Chem 35: 1318-20 (1992) BindingDB Entry DOI: 10.7270/Q2W959T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Canada Curated by ChEMBL | Assay Description Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group) | J Med Chem 35: 1318-20 (1992) BindingDB Entry DOI: 10.7270/Q2W959T5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Products Ltd. Curated by ChEMBL | Assay Description Binding activity against HIV-1 Protease | J Med Chem 34: 3340-2 (1991) BindingDB Entry DOI: 10.7270/Q2B858Q3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Products Ltd. Curated by ChEMBL | Assay Description Binding activity against HIV-1 Protease | J Med Chem 34: 3340-2 (1991) BindingDB Entry DOI: 10.7270/Q2B858Q3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Canada Curated by ChEMBL | Assay Description Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group) | J Med Chem 35: 1318-20 (1992) BindingDB Entry DOI: 10.7270/Q2W959T5 | |||||||||||
More data for this Ligand-Target Pair |