BindingDB PrimarySearch

Found 8 hits of ic50 for monomerid = 50022784
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET transfected in HEK cells				Bioorg Med Chem Lett 18: 6151-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.013 BindingDB Entry DOI: 10.7270/Q2JS9Q86
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in HEK cells				Bioorg Med Chem Lett 18: 4495-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.050 BindingDB Entry DOI: 10.7270/Q2VH5NP8
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in HEK cells				Bioorg Med Chem Lett 18: 4495-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.050 BindingDB Entry DOI: 10.7270/Q2VH5NP8
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT transfected in HEK cells				Bioorg Med Chem Lett 18: 6151-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.013 BindingDB Entry DOI: 10.7270/Q2JS9Q86
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 18: 6151-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.013 BindingDB Entry DOI: 10.7270/Q2JS9Q86
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at human DAT transfected in HEK cells				Bioorg Med Chem Lett 18: 6151-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.013 BindingDB Entry DOI: 10.7270/Q2JS9Q86
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at human DAT expressed in HEK cells				Bioorg Med Chem Lett 18: 4495-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.050 BindingDB Entry DOI: 10.7270/Q2VH5NP8
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50022784 ((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...) Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Curated by ChEMBL					Assay Description Inhibitory activity against Opioid receptor like 1 expressed in HEK-293 cells				Bioorg Med Chem Lett 14: 4083-5 (2004) Article DOI: 10.1016/j.bmcl.2004.05.018 BindingDB Entry DOI: 10.7270/Q21N80K4
Johnson and Johnson Pharmaceutical Curated by ChEMBL					More data for this Ligand-Target Pair