Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.98 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 20.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 20.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 23.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Bocillin FL binding to Streptococcus pneumoniae isolate 8865 PBP2b | Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/AAC.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 23.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 23.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 23.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 29.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 32.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 35.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 47.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 59.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 83.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 92.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP1A | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 287 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 331 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 448 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Bocillin FL binding to PBP2b in laboratory-derived Streptococcus pneumoniae isolate R6 | Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/AAC.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 466 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 532 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 789 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2B | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2x (Streptococcus pneumoniae) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2X | Antimicrob Agents Chemother 53: 2176-80 (2009) Article DOI: 10.1128/AAC.01566-08 BindingDB Entry DOI: 10.7270/Q24B345B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Bocillin FL binding to PBP2b Thr446Ala mutant in laboratory-derived Streptococcus pneumoniae isolate R6 | Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/AAC.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Bocillin FL binding to PBP2b Thr446Ala/Ala-619-Gly mutant in laboratory-derived Streptococcus pneumoniae isolate R6 | Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/AAC.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Binding affinity to methicillin-, linezolid-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 2149A PBP2a by competit... | Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/AAC.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Bocillin FL binding to PBP2b PBP2b 443SSNA mutant in Streptococcus pneumoniae isolate 8009 harboring E333G, N470K, E476G, T489S, E506D,... | Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/AAC.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Streptococcus pneumoniae isolate 8882 Bocillin FL binding to PBP2b 443SSNA mutant | Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/AAC.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile salt export pump (Homo sapiens (Human)) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-... | Drug Metab Dispos 40: 2332-41 (2012) Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Binding affinity to against methicillin-, daptomycin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 25 PBP2a by co... | Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/AAC.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Binding affinity to methicillin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 1287 PBP2a by competitive binding a... | Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/AAC.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description Inhibition of Bocillin FL binding to PBP2b in Streptococcus pneumoniae isolate 8819 harboring E333G, I361L, E369D, S412P, N422Y, T426K, Q427L, Q438E,... | Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/AAC.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 8 (Mus musculus) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wilkes University Curated by ChEMBL | Assay Description Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 mins | Drug Metab Dispos 41: 791-800 (2013) Article DOI: 10.1124/dmd.112.049569 BindingDB Entry DOI: 10.7270/Q2TF003W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.91E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Binding affinity to methicillin-resistant, heteroresistant vancomycin-intermediate, beta-lactamase-negative Staphylococcus aureus 873 PBP2a by compet... | Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/AAC.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptidase (Staphylococcus aureus) | BDBM50022787 ((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.91E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center Curated by ChEMBL | Assay Description Binding affinity to methicillin-, vancomycin-resistant, beta-lactamase-positive Staphylococcus aureus 510 PBP2a by competitive binding assay | Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/AAC.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6 | |||||||||||
More data for this Ligand-Target Pair |