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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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Ki
IC50
Kd
EC50
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Compile Data Set for Download or QSAR
Found
4
hits of ic50 for monomerid = 50024294
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
BDBM50024294
(SP-600125)
Show SMILES
Oc1c2cccc3N=Nc(c23)c2ccccc12 |c:7|
Show InChI
InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7,17H
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
40
n/a
n/a
n/a
n/a
n/a
n/a
Eberhard Karls Universit£t T£bingen
Curated by
ChEMBL
Assay Description
Inhibition of JNK1 (unknown origin) by time-resolved fluorescence assay
J Med Chem
58:
72
-
95
(2015)
Article DOI:
10.1021/jm501212r
BindingDB Entry DOI:
10.7270/Q2JH3NVZ
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
BDBM50024294
(SP-600125)
Show SMILES
Oc1c2cccc3N=Nc(c23)c2ccccc12 |c:7|
Show InChI
InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7,17H
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
40
n/a
n/a
n/a
n/a
n/a
n/a
Eberhard Karls Universit£t T£bingen
Curated by
ChEMBL
Assay Description
Inhibition of JNK2 (unknown origin) by time-resolved fluorescence assay
J Med Chem
58:
72
-
95
(2015)
Article DOI:
10.1021/jm501212r
BindingDB Entry DOI:
10.7270/Q2JH3NVZ
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
BDBM50024294
(SP-600125)
Show SMILES
Oc1c2cccc3N=Nc(c23)c2ccccc12 |c:7|
Show InChI
InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7,17H
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
90
n/a
n/a
n/a
n/a
n/a
n/a
Eberhard Karls Universit£t T£bingen
Curated by
ChEMBL
Assay Description
Inhibition of JNK3 (unknown origin) by time-resolved fluorescence assay
J Med Chem
58:
72
-
95
(2015)
Article DOI:
10.1021/jm501212r
BindingDB Entry DOI:
10.7270/Q2JH3NVZ
More data for this
Ligand-Target Pair
Dual specificity protein kinase TTK
(Homo sapiens (Human))
BDBM50024294
(SP-600125)
Show SMILES
Oc1c2cccc3N=Nc(c23)c2ccccc12 |c:7|
Show InChI
InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7,17H
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
2.50E+3
n/a
n/a
n/a
n/a
n/a
n/a
University Health Network
Curated by
ChEMBL
Assay Description
Inhibition of GST-fused full length human TTK compound pre-incubated for 15 mins prior ATP addition by MBP-based assay
Bioorg Med Chem
22:
4968
-
97
(2014)
Article DOI:
10.1016/j.bmc.2014.06.027
BindingDB Entry DOI:
10.7270/Q2K35WB2
More data for this
Ligand-Target Pair
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