BindingDB PrimarySearch

Found 6 hits of ic50 for monomerid = 50041419
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50041419 (1,2,5,8-tetrahydroxy-9,10-anthracenedione \| 1,2,5,...) Show SMILES Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CK2 alpha (unknown origin) relative to control				Citation and Details Article DOI: 10.1016/j.bmc.2020.115674 BindingDB Entry DOI: 10.7270/Q2TM7FQQ
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Integrase (Human immunodeficiency virus 1)	BDBM50041419 (1,2,5,8-tetrahydroxy-9,10-anthracenedione \| 1,2,5,...) Show SMILES Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transfer				J Med Chem 43: 2100-14 (2000) BindingDB Entry DOI: 10.7270/Q27D2VTS
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50041419 (1,2,5,8-tetrahydroxy-9,10-anthracenedione \| 1,2,5,...) Show SMILES Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessing				J Med Chem 43: 2100-14 (2000) BindingDB Entry DOI: 10.7270/Q27D2VTS
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM50041419 (1,2,5,8-tetrahydroxy-9,10-anthracenedione \| 1,2,5,...) Show SMILES Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	7.8	23
University of Michigan					Assay Description Enzyme activity assay using human and murine PAI-1.				J Biol Chem 285: 7892-902 (2010) Article DOI: 10.1074/jbc.M109.067967 BindingDB Entry DOI: 10.7270/Q2ZC81FC
University of Michigan					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50041419 (1,2,5,8-tetrahydroxy-9,10-anthracenedione \| 1,2,5,...) Show SMILES Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2021.116558 BindingDB Entry DOI: 10.7270/Q27948Q4
TBA					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50041419 (1,2,5,8-tetrahydroxy-9,10-anthracenedione \| 1,2,5,...) Show SMILES Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116292 BindingDB Entry DOI: 10.7270/Q2222ZH0
TBA					More data for this Ligand-Target Pair