Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 50041897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50041897 (CHEMBL3358921) Show SMILES Cc1c(CC(O)(CC(C)(C)c2cc(F)ccc2C)C(F)(F)F)[nH]c2cnccc12 Show InChI InChI=1S/C22H24F4N2O/c1-13-5-6-15(23)9-17(13)20(3,4)12-21(29,22(24,25)26)10-18-14(2)16-7-8-27-11-19(16)28-18/h5-9,11,28-29H,10,12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GR in HFF cells assessed as suppression of IL-1-induced IL-6 production				ACS Med Chem Lett 5: 1318-23 (2014) Article DOI: 10.1021/ml500387y BindingDB Entry DOI: 10.7270/Q2639RCZ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50041897 (CHEMBL3358921) Show SMILES Cc1c(CC(O)(CC(C)(C)c2cc(F)ccc2C)C(F)(F)F)[nH]c2cnccc12 Show InChI InChI=1S/C22H24F4N2O/c1-13-5-6-15(23)9-17(13)20(3,4)12-21(29,22(24,25)26)10-18-14(2)16-7-8-27-11-19(16)28-18/h5-9,11,28-29H,10,12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of RU-486 from GR (unknown origin) by fluorescence polarization assay				ACS Med Chem Lett 5: 1318-23 (2014) Article DOI: 10.1021/ml500387y BindingDB Entry DOI: 10.7270/Q2639RCZ
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50041897 (CHEMBL3358921) Show SMILES Cc1c(CC(O)(CC(C)(C)c2cc(F)ccc2C)C(F)(F)F)[nH]c2cnccc12 Show InChI InChI=1S/C22H24F4N2O/c1-13-5-6-15(23)9-17(13)20(3,4)12-21(29,22(24,25)26)10-18-14(2)16-7-8-27-11-19(16)28-18/h5-9,11,28-29H,10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)-coumarin as substrate after 30 mins by fluorescence assay				ACS Med Chem Lett 5: 1318-23 (2014) Article DOI: 10.1021/ml500387y BindingDB Entry DOI: 10.7270/Q2639RCZ
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50041897 (CHEMBL3358921) Show SMILES Cc1c(CC(O)(CC(C)(C)c2cc(F)ccc2C)C(F)(F)F)[nH]c2cnccc12 Show InChI InChI=1S/C22H24F4N2O/c1-13-5-6-15(23)9-17(13)20(3,4)12-21(29,22(24,25)26)10-18-14(2)16-7-8-27-11-19(16)28-18/h5-9,11,28-29H,10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)-coumarin as substrate after 30 mins by fluorescence assay				ACS Med Chem Lett 5: 1318-23 (2014) Article DOI: 10.1021/ml500387y BindingDB Entry DOI: 10.7270/Q2639RCZ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50041897 (CHEMBL3358921) Show SMILES Cc1c(CC(O)(CC(C)(C)c2cc(F)ccc2C)C(F)(F)F)[nH]c2cnccc12 Show InChI InChI=1S/C22H24F4N2O/c1-13-5-6-15(23)9-17(13)20(3,4)12-21(29,22(24,25)26)10-18-14(2)16-7-8-27-11-19(16)28-18/h5-9,11,28-29H,10,12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of tetramethylrhodamine-labeled dexamethasone from PR (unknown origin) by fluorescence polarization assay				ACS Med Chem Lett 5: 1318-23 (2014) Article DOI: 10.1021/ml500387y BindingDB Entry DOI: 10.7270/Q2639RCZ
					More data for this Ligand-Target Pair