Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50043024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043024 (CHEMBL3355034 | US9718825, Example 310) Show SMILES CC(C)COc1nc(nc2[nH]nc(N)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)cc1 Show InChI InChI=1S/C21H20Cl2N6O3S/c1-11(2)10-32-21-17-18(24)27-28-20(17)25-19(26-21)12-3-6-14(7-4-12)29-33(30,31)16-9-13(22)5-8-15(16)23/h3-9,11,29H,10H2,1-2H3,(H3,24,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of SGK1 (unknown origin) assessed as substrate phosphorylation				ACS Med Chem Lett 6: 19-20 (2015) Article DOI: 10.1021/ml500480n BindingDB Entry DOI: 10.7270/Q2PZ5BFB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043024 (CHEMBL3355034 | US9718825, Example 310) Show SMILES CC(C)COc1nc(nc2[nH]nc(N)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)cc1 Show InChI InChI=1S/C21H20Cl2N6O3S/c1-11(2)10-32-21-17-18(24)27-28-20(17)25-19(26-21)12-3-6-14(7-4-12)29-33(30,31)16-9-13(22)5-8-15(16)23/h3-9,11,29H,10H2,1-2H3,(H3,24,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	n/a
SANOFI US Patent					Assay Description The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...				US Patent US9718825 (2017) BindingDB Entry DOI: 10.7270/Q2VM4F82
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50043024 (CHEMBL3355034 | US9718825, Example 310) Show SMILES CC(C)COc1nc(nc2[nH]nc(N)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)cc1 Show InChI InChI=1S/C21H20Cl2N6O3S/c1-11(2)10-32-21-17-18(24)27-28-20(17)25-19(26-21)12-3-6-14(7-4-12)29-33(30,31)16-9-13(22)5-8-15(16)23/h3-9,11,29H,10H2,1-2H3,(H3,24,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Dart Neuroscience LLC Curated by ChEMBL					Assay Description Inhibition of recombinant SGK1 (unknown origin) expressed in U2OS cells by cellular activity assay				ACS Med Chem Lett 6: 19-20 (2015) Article DOI: 10.1021/ml500480n BindingDB Entry DOI: 10.7270/Q2PZ5BFB
					More data for this Ligand-Target Pair