Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50049243 (5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazoli...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern Ohio Universities Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-B after 15 mins | Bioorg Med Chem Lett 20: 5295-8 (2010) Article DOI: 10.1016/j.bmcl.2010.06.128 BindingDB Entry DOI: 10.7270/Q2S46SX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50049243 (5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazoli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.74E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Industry-Academic Cooperation Foundation, Chosun University US Patent | Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s... | US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50049243 (5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazoli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of PGDH (unknown origin) | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair |