Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribonucleoside-diphosphate reductase large subunit/subunit M2 (Homo sapiens (Human)) | BDBM50050828 ((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3-methyl-2-[3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bio-M£ga/Boehringer Ingelheim Research Inc. Curated by ChEMBL | Assay Description Inhibitory effect was evaluated on Herpes simplex virus (HSV) ribonucleotide reductase (RR) enzyme. | J Med Chem 39: 4173-80 (1996) Article DOI: 10.1021/jm960324r BindingDB Entry DOI: 10.7270/Q28W3DZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribonucleoside-diphosphate reductase large subunit (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...) | BDBM50050828 ((S)-2-[(S)-3-Carboxy-2-((S)-2-{(S)-3-methyl-2-[3-(...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bio-Méga/Boehringer Ingelheim Research Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Herpes simplex virus (HSV) ribonucleotide reductase (RR) | J Med Chem 39: 2178-87 (1996) Article DOI: 10.1021/jm950825x BindingDB Entry DOI: 10.7270/Q2BG2N22 | |||||||||||
More data for this Ligand-Target Pair |