Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50055851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50055851 (CHEMBL3325792) Show SMILES CCCC(=O)c1cnn(c1C)-c1ccc(NC(=O)c2cn(CC(=O)N3CCN(C)CC3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C31H33F3N6O3/c1-4-5-28(41)25-17-35-40(20(25)2)23-9-7-22(8-10-23)36-30(43)26-18-39(19-29(42)38-14-12-37(3)13-15-38)27-11-6-21(16-24(26)27)31(32,33)34/h6-11,16-18H,4-5,12-15,19H2,1-3H3,(H,36,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor in Sprague-Dawley rat platelet rich plasma assessed as inhibition of ADP-induced aggregation				J Med Chem 57: 7293-316 (2014) Article DOI: 10.1021/jm500588w BindingDB Entry DOI: 10.7270/Q2D79D21
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Rattus norvegicus)	BDBM50055851 (CHEMBL3325792) Show SMILES CCCC(=O)c1cnn(c1C)-c1ccc(NC(=O)c2cn(CC(=O)N3CCN(C)CC3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C31H33F3N6O3/c1-4-5-28(41)25-17-35-40(20(25)2)23-9-7-22(8-10-23)36-30(43)26-18-39(19-29(42)38-14-12-37(3)13-15-38)27-11-6-21(16-24(26)27)31(32,33)34/h6-11,16-18H,4-5,12-15,19H2,1-3H3,(H,36,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor in Sprague-Dawley rat platelet rich plasma assessed as inhibition of ADP-induced aggregation				J Med Chem 57: 7293-316 (2014) Article DOI: 10.1021/jm500588w BindingDB Entry DOI: 10.7270/Q2D79D21
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50055851 (CHEMBL3325792) Show SMILES CCCC(=O)c1cnn(c1C)-c1ccc(NC(=O)c2cn(CC(=O)N3CCN(C)CC3)c3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C31H33F3N6O3/c1-4-5-28(41)25-17-35-40(20(25)2)23-9-7-22(8-10-23)36-30(43)26-18-39(19-29(42)38-14-12-37(3)13-15-38)27-11-6-21(16-24(26)27)31(32,33)34/h6-11,16-18H,4-5,12-15,19H2,1-3H3,(H,36,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor in human platelet rich plasma assessed as inhibition of ADP-induced aggregation				J Med Chem 57: 7293-316 (2014) Article DOI: 10.1021/jm500588w BindingDB Entry DOI: 10.7270/Q2D79D21
					More data for this Ligand-Target Pair