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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50063577   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 1


(Homo sapiens (Human))
BDBM50063577
PNG
(CHEMBL3398593)
Show SMILES Oc1ccc(NC(=O)[C@@H]2CCN(CC(=O)N3CCN(CC3)c3ccc(cc3)-c3cccc(F)c3)C2)cc1Cl |r|
Show InChI InChI=1/C29H30ClFN4O3/c30-26-17-24(6-9-27(26)36)32-29(38)22-10-11-33(18-22)19-28(37)35-14-12-34(13-15-35)25-7-4-20(5-8-25)21-2-1-3-23(31)16-21/h1-9,16-17,22,36H,10-15,18-19H2,(H,32,38)/t22-/s2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of non-activated Erk2 (unknown origin) using activating Mek1 and peptide substrate by coupled Erk2 assay


Bioorg Med Chem Lett 25: 1627-9 (2015)


Article DOI: 10.1016/j.bmcl.2015.01.049
BindingDB Entry DOI: 10.7270/Q2BK1F1S
More data for this
Ligand-Target Pair