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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50063675   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase EZH2


(Homo sapiens (Human))		BDBM50063675
PNG
(CHEMBL3397326)
Show SMILES CN1CCn2nc(CNC(=O)[C@@H](N)CCSC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3cnc4c(N)ncnc34)cc2C1 |r|
Show InChI InChI=1S/C22H32N10O4S/c1-30-3-4-32-13(8-30)6-12(29-32)7-25-21(35)14(23)2-5-37-9-15-17(33)18(34)22(36-15)31-11-28-16-19(24)26-10-27-20(16)31/h6,10-11,14-15,17-18,22,33-34H,2-5,7-9,23H2,1H3,(H,25,35)(H2,24,26,27)/t14-,15+,17+,18+,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...

Bioorg Med Chem Lett 25: 1532-7 (2015)


Article DOI: 10.1016/j.bmcl.2015.02.017
BindingDB Entry DOI: 10.7270/Q2TM7CSS
More data for this
Ligand-Target Pair