Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 50065275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50065275 (3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...) Show SMILES CC(C)(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H27NO2/c1-22(2,3)17-12-14(13-18(20(17)25)23(4,5)6)11-16-15-9-7-8-10-19(15)24-21(16)26/h7-13,25H,1-6H3,(H,24,26)/b16-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Mus musculus)	BDBM50065275 (3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...) Show SMILES CC(C)(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H27NO2/c1-22(2,3)17-12-14(13-18(20(17)25)23(4,5)6)11-16-15-9-7-8-10-19(15)24-21(16)26/h7-13,25H,1-6H3,(H,24,26)/b16-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50065275 (3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...) Show SMILES CC(C)(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H27NO2/c1-22(2,3)17-12-14(13-18(20(17)25)23(4,5)6)11-16-15-9-7-8-10-19(15)24-21(16)26/h7-13,25H,1-6H3,(H,24,26)/b16-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptor				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50065275 (3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...) Show SMILES CC(C)(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H27NO2/c1-22(2,3)17-12-14(13-18(20(17)25)23(4,5)6)11-16-15-9-7-8-10-19(15)24-21(16)26/h7-13,25H,1-6H3,(H,24,26)/b16-11-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50065275 (3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...) Show SMILES CC(C)(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H27NO2/c1-22(2,3)17-12-14(13-18(20(17)25)23(4,5)6)11-16-15-9-7-8-10-19(15)24-21(16)26/h7-13,25H,1-6H3,(H,24,26)/b16-11-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of HER2 (unknown origin)				J Med Chem 51: 3367-77 (2008) Article DOI: 10.1021/jm7013875 BindingDB Entry DOI: 10.7270/Q2086532
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50065275 (3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...) Show SMILES CC(C)(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(c1O)C(C)(C)C Show InChI InChI=1S/C23H27NO2/c1-22(2,3)17-12-14(13-18(20(17)25)23(4,5)6)11-16-15-9-7-8-10-19(15)24-21(16)26/h7-13,25H,1-6H3,(H,24,26)/b16-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc. Curated by ChEMBL					Assay Description Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).				J Med Chem 41: 2588-603 (1998) Article DOI: 10.1021/jm980123i BindingDB Entry DOI: 10.7270/Q2G73CTT
					More data for this Ligand-Target Pair