new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50092884   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor AP-1


(Homo sapiens (Human))
BDBM50092884
PNG
(CHEMBL132457 | N-(3,5-Bis-trifluoromethyl-phenyl)-...)
Show SMILES FC(F)(F)c1cc(NC(=O)c2ccc(Cl)cc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C16H7ClF9NO/c17-9-1-2-11(12(6-9)16(24,25)26)13(28)27-10-4-7(14(18,19)20)3-8(5-10)15(21,22)23/h1-6H,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assay


J Med Chem 57: 6930-48 (2014)


Article DOI: 10.1021/jm5004733
BindingDB Entry DOI: 10.7270/Q2222WDT
More data for this
Ligand-Target Pair
Transcription factor AP-1


(Homo sapiens (Human))
BDBM50092884
PNG
(CHEMBL132457 | N-(3,5-Bis-trifluoromethyl-phenyl)-...)
Show SMILES FC(F)(F)c1cc(NC(=O)c2ccc(Cl)cc2C(F)(F)F)cc(c1)C(F)(F)F
Show InChI InChI=1S/C16H7ClF9NO/c17-9-1-2-11(12(6-9)16(24,25)26)13(28)27-10-4-7(14(18,19)20)3-8(5-10)15(21,22)23/h1-6H,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells


J Med Chem 43: 3995-4004 (2000)


BindingDB Entry DOI: 10.7270/Q26M363N
More data for this
Ligand-Target Pair