Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human)) | BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value). | J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human)) | BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value). | J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2 | |||||||||||
More data for this Ligand-Target Pair |