Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against adenosine kinase | J Med Chem 47: 3463-82 (2004) Article DOI: 10.1021/jm040031v BindingDB Entry DOI: 10.7270/Q2NC61ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Tested for inhibitory activity against AK in an in vitro cell-free enzyme assay | J Med Chem 43: 4781-6 (2000) BindingDB Entry DOI: 10.7270/Q289154F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Rattus norvegicus (rat)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro inhibition of Adenosine kinase (AK) | J Med Chem 44: 2133-8 (2001) BindingDB Entry DOI: 10.7270/Q25D8R47 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of human adenosine kinase assessed as reduction in conversion of adenosine to AMP | J Med Chem 59: 6860-77 (2016) Article DOI: 10.1021/acs.jmedchem.6b00689 BindingDB Entry DOI: 10.7270/Q2TF01TQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Rattus norvegicus (rat)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assay | Bioorg Med Chem Lett 11: 83-6 (2001) BindingDB Entry DOI: 10.7270/Q2PC31NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans Curated by ChEMBL | Assay Description Inhibition of adenosine kinase (unknown origin) | Eur J Med Chem 95: 76-95 (2015) Article DOI: 10.1016/j.ejmech.2015.03.029 BindingDB Entry DOI: 10.7270/Q2PR7XP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER AG Curated by ChEMBL | Assay Description Inhibitory activity against human adenosine kinase expressed in E. coli | Bioorg Med Chem Lett 14: 1997-2000 (2004) Article DOI: 10.1016/j.bmcl.2004.01.082 BindingDB Entry DOI: 10.7270/Q2GQ6X6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of intact cells | Bioorg Med Chem Lett 11: 2071-4 (2001) BindingDB Entry DOI: 10.7270/Q2CN735Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 43.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro concentration required for 50% inhibition against Adenosine Kinase (AK) in the presence of intact cells | Bioorg Med Chem Lett 11: 2071-4 (2001) BindingDB Entry DOI: 10.7270/Q2CN735Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Rattus norvegicus (rat)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory activity against intact cell adenosine kinase by ADO phosphorylation assay | Bioorg Med Chem Lett 11: 83-6 (2001) BindingDB Entry DOI: 10.7270/Q2PC31NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Homo sapiens (Human)) | BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of adenosine phosphorylation in confluent IMR-32 (human neuroblastoma) cells. | J Med Chem 44: 2133-8 (2001) BindingDB Entry DOI: 10.7270/Q25D8R47 | |||||||||||
More data for this Ligand-Target Pair |