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Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 50105110   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50105110
PNG
(4-(3-Phenyl-propyl)-piperazine-1-carboxylic acid 2...)
Show SMILES O=C(OCCc1ccc(cc1)C#N)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C23H27N3O2/c24-19-22-10-8-21(9-11-22)12-18-28-23(27)26-16-14-25(15-17-26)13-4-7-20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-18H2
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n/an/a 280n/an/an/an/an/an/a



F-59000 Lille

Curated by ChEMBL


Assay Description
Inhibition of histamine H1 receptor


J Med Chem 44: 3391-401 (2001)


BindingDB Entry DOI: 10.7270/Q2057GN9
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50105110
PNG
(4-(3-Phenyl-propyl)-piperazine-1-carboxylic acid 2...)
Show SMILES O=C(OCCc1ccc(cc1)C#N)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C23H27N3O2/c24-19-22-10-8-21(9-11-22)12-18-28-23(27)26-16-14-25(15-17-26)13-4-7-20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-18H2
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n/an/a 800n/an/an/an/an/an/a



F-59000 Lille

Curated by ChEMBL


Assay Description
Binding affinity against mu opiate receptor


J Med Chem 44: 3391-401 (2001)


BindingDB Entry DOI: 10.7270/Q2057GN9
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50105110
PNG
(4-(3-Phenyl-propyl)-piperazine-1-carboxylic acid 2...)
Show SMILES O=C(OCCc1ccc(cc1)C#N)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C23H27N3O2/c24-19-22-10-8-21(9-11-22)12-18-28-23(27)26-16-14-25(15-17-26)13-4-7-20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-18H2
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n/an/a 854n/an/an/an/an/an/a



F-59000 Lille

Curated by ChEMBL


Assay Description
Inhibition of human 5-hydroxytryptamine 2A receptor


J Med Chem 44: 3391-401 (2001)


BindingDB Entry DOI: 10.7270/Q2057GN9
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50105110
PNG
(4-(3-Phenyl-propyl)-piperazine-1-carboxylic acid 2...)
Show SMILES O=C(OCCc1ccc(cc1)C#N)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C23H27N3O2/c24-19-22-10-8-21(9-11-22)12-18-28-23(27)26-16-14-25(15-17-26)13-4-7-20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-18H2
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n/an/a 1.41E+3n/an/an/an/an/an/a



F-59000 Lille

Curated by ChEMBL


Assay Description
Inhibition of human dopamine receptor D4.4


J Med Chem 44: 3391-401 (2001)


BindingDB Entry DOI: 10.7270/Q2057GN9
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50105110
PNG
(4-(3-Phenyl-propyl)-piperazine-1-carboxylic acid 2...)
Show SMILES O=C(OCCc1ccc(cc1)C#N)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C23H27N3O2/c24-19-22-10-8-21(9-11-22)12-18-28-23(27)26-16-14-25(15-17-26)13-4-7-20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-18H2
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antibodypedia
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n/an/a 1.57E+3n/an/an/an/an/an/a



F-59000 Lille

Curated by ChEMBL


Assay Description
Inhibition of human 5-hydroxytryptamine 1A receptor


J Med Chem 44: 3391-401 (2001)


BindingDB Entry DOI: 10.7270/Q2057GN9
More data for this
Ligand-Target Pair