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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50113480   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50113480
PNG
(CHEMBL3603927 | US10246432, Example 5 | US10584111...)
Show SMILES Clc1cc(cc(c1)-c1cc(ncn1)-c1cccnn1)C#N
Show InChI InChI=1S/C15H8ClN5/c16-12-5-10(8-17)4-11(6-12)14-7-15(19-9-18-14)13-2-1-3-20-21-13/h1-7,9H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Heptares Therapeutics Ltd.

Curated by ChEMBL


Assay Description
Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...

J Med Chem 58: 6653-64 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00892
BindingDB Entry DOI: 10.7270/Q2H70HMZ
More data for this
Ligand-Target Pair