Found 4 hits of ic50 for monomerid = 50130520 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130520
(CHEMBL3634328)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)N1C(=O)Cc2ccccc12 Show InChI InChI=1S/C29H30N2O4/c32-24(20-35-27-13-7-5-11-25(27)29(34)21-8-2-1-3-9-21)19-30-16-14-23(15-17-30)31-26-12-6-4-10-22(26)18-28(31)33/h1-13,23-24,32H,14-20H2 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130520
(CHEMBL3634328)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)N1C(=O)Cc2ccccc12 Show InChI InChI=1S/C29H30N2O4/c32-24(20-35-27-13-7-5-11-25(27)29(34)21-8-2-1-3-9-21)19-30-16-14-23(15-17-30)31-26-12-6-4-10-22(26)18-28(31)33/h1-13,23-24,32H,14-20H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130520
(CHEMBL3634328)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)N1C(=O)Cc2ccccc12 Show InChI InChI=1S/C29H30N2O4/c32-24(20-35-27-13-7-5-11-25(27)29(34)21-8-2-1-3-9-21)19-30-16-14-23(15-17-30)31-26-12-6-4-10-22(26)18-28(31)33/h1-13,23-24,32H,14-20H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130520
(CHEMBL3634328)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(CC1)N1C(=O)Cc2ccccc12 Show InChI InChI=1S/C29H30N2O4/c32-24(20-35-27-13-7-5-11-25(27)29(34)21-8-2-1-3-9-21)19-30-16-14-23(15-17-30)31-26-12-6-4-10-22(26)18-28(31)33/h1-13,23-24,32H,14-20H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
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