Found 4 hits of ic50 for monomerid = 50130530 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130530
(CHEMBL3634337)Show SMILES OC(COc1ccccc1C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C23H25F3N2O3/c24-23(25,26)20-7-3-4-8-21(20)31-15-18(29)14-27-11-9-17(10-12-27)28-13-16-5-1-2-6-19(16)22(28)30/h1-8,17-18,29H,9-15H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130530
(CHEMBL3634337)Show SMILES OC(COc1ccccc1C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C23H25F3N2O3/c24-23(25,26)20-7-3-4-8-21(20)31-15-18(29)14-27-11-9-17(10-12-27)28-13-16-5-1-2-6-19(16)22(28)30/h1-8,17-18,29H,9-15H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130530
(CHEMBL3634337)Show SMILES OC(COc1ccccc1C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C23H25F3N2O3/c24-23(25,26)20-7-3-4-8-21(20)31-15-18(29)14-27-11-9-17(10-12-27)28-13-16-5-1-2-6-19(16)22(28)30/h1-8,17-18,29H,9-15H2 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130530
(CHEMBL3634337)Show SMILES OC(COc1ccccc1C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C23H25F3N2O3/c24-23(25,26)20-7-3-4-8-21(20)31-15-18(29)14-27-11-9-17(10-12-27)28-13-16-5-1-2-6-19(16)22(28)30/h1-8,17-18,29H,9-15H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
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