Found 4 hits of ic50 for monomerid = 50130533 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130533
(CHEMBL3632693)Show SMILES COc1cc(ccc1OCC(O)CN1CCC(CC1)N1Cc2ccccc2C1=O)C(F)(F)F Show InChI InChI=1S/C24H27F3N2O4/c1-32-22-12-17(24(25,26)27)6-7-21(22)33-15-19(30)14-28-10-8-18(9-11-28)29-13-16-4-2-3-5-20(16)23(29)31/h2-7,12,18-19,30H,8-11,13-15H2,1H3 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130533
(CHEMBL3632693)Show SMILES COc1cc(ccc1OCC(O)CN1CCC(CC1)N1Cc2ccccc2C1=O)C(F)(F)F Show InChI InChI=1S/C24H27F3N2O4/c1-32-22-12-17(24(25,26)27)6-7-21(22)33-15-19(30)14-28-10-8-18(9-11-28)29-13-16-4-2-3-5-20(16)23(29)31/h2-7,12,18-19,30H,8-11,13-15H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130533
(CHEMBL3632693)Show SMILES COc1cc(ccc1OCC(O)CN1CCC(CC1)N1Cc2ccccc2C1=O)C(F)(F)F Show InChI InChI=1S/C24H27F3N2O4/c1-32-22-12-17(24(25,26)27)6-7-21(22)33-15-19(30)14-28-10-8-18(9-11-28)29-13-16-4-2-3-5-20(16)23(29)31/h2-7,12,18-19,30H,8-11,13-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130533
(CHEMBL3632693)Show SMILES COc1cc(ccc1OCC(O)CN1CCC(CC1)N1Cc2ccccc2C1=O)C(F)(F)F Show InChI InChI=1S/C24H27F3N2O4/c1-32-22-12-17(24(25,26)27)6-7-21(22)33-15-19(30)14-28-10-8-18(9-11-28)29-13-16-4-2-3-5-20(16)23(29)31/h2-7,12,18-19,30H,8-11,13-15H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |