Found 4 hits of ic50 for monomerid = 50130534 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130534
(CHEMBL3632694)Show SMILES OC(COCc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C24H27F3N2O3/c25-24(26,27)19-7-5-17(6-8-19)15-32-16-21(30)14-28-11-9-20(10-12-28)29-13-18-3-1-2-4-22(18)23(29)31/h1-8,20-21,30H,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130534
(CHEMBL3632694)Show SMILES OC(COCc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C24H27F3N2O3/c25-24(26,27)19-7-5-17(6-8-19)15-32-16-21(30)14-28-11-9-20(10-12-28)29-13-18-3-1-2-4-22(18)23(29)31/h1-8,20-21,30H,9-16H2 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130534
(CHEMBL3632694)Show SMILES OC(COCc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C24H27F3N2O3/c25-24(26,27)19-7-5-17(6-8-19)15-32-16-21(30)14-28-11-9-20(10-12-28)29-13-18-3-1-2-4-22(18)23(29)31/h1-8,20-21,30H,9-16H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130534
(CHEMBL3632694)Show SMILES OC(COCc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)N1Cc2ccccc2C1=O Show InChI InChI=1S/C24H27F3N2O3/c25-24(26,27)19-7-5-17(6-8-19)15-32-16-21(30)14-28-11-9-20(10-12-28)29-13-18-3-1-2-4-22(18)23(29)31/h1-8,20-21,30H,9-16H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005 BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this Ligand-Target Pair | |