Found 4 hits of ic50 for monomerid = 50130536 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130536
(CHEMBL3632696)Show SMILES OC(COc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)NC(=O)c1ccccc1 Show InChI InChI=1S/C22H25F3N2O3/c23-22(24,25)17-6-8-20(9-7-17)30-15-19(28)14-27-12-10-18(11-13-27)26-21(29)16-4-2-1-3-5-16/h1-9,18-19,28H,10-15H2,(H,26,29) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130536
(CHEMBL3632696)Show SMILES OC(COc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)NC(=O)c1ccccc1 Show InChI InChI=1S/C22H25F3N2O3/c23-22(24,25)17-6-8-20(9-7-17)30-15-19(28)14-27-12-10-18(11-13-27)26-21(29)16-4-2-1-3-5-16/h1-9,18-19,28H,10-15H2,(H,26,29) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130536
(CHEMBL3632696)Show SMILES OC(COc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)NC(=O)c1ccccc1 Show InChI InChI=1S/C22H25F3N2O3/c23-22(24,25)17-6-8-20(9-7-17)30-15-19(28)14-27-12-10-18(11-13-27)26-21(29)16-4-2-1-3-5-16/h1-9,18-19,28H,10-15H2,(H,26,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130536
(CHEMBL3632696)Show SMILES OC(COc1ccc(cc1)C(F)(F)F)CN1CCC(CC1)NC(=O)c1ccccc1 Show InChI InChI=1S/C22H25F3N2O3/c23-22(24,25)17-6-8-20(9-7-17)30-15-19(28)14-27-12-10-18(11-13-27)26-21(29)16-4-2-1-3-5-16/h1-9,18-19,28H,10-15H2,(H,26,29) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Search and Browse
