Compile Data Set for Download or QSAR

Found 14 hits of ic50 for monomerid = 50133841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR Y290L mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR D302N mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR D302A mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR H306A mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR L300A mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR F313L mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR M24I mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR Y284L mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR F309Q mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR F309L mutant expressed in COS-7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR Q208E mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50133841 (1-(2,6-difluorobenzyl)-5-((benzyl(methyl)amino)met...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1 Show InChI InChI=1S/C34H26F2N4O4S/c1-37(19-22-9-4-2-5-10-22)20-27-30-32(41)39(24-11-6-3-7-12-24)34(42)38(21-26-28(35)13-8-14-29(26)36)33(30)45-31(27)23-15-17-25(18-16-23)40(43)44/h2-18H,19-21H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR H306E mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
					More data for this Ligand-Target Pair