Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisomal acyl-coenzyme A oxidase 1 (Rattus norvegicus) | BDBM50138599 (CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics Curated by ChEMBL | Assay Description Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation. | Bioorg Med Chem Lett 14: 549-52 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisomal acyl-coenzyme A oxidase 1 (Rattus norvegicus) | BDBM50138599 (CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of palmitoyl-CoA oxidation in rat heart mitochondria | Bioorg Med Chem Lett 14: 6017-21 (2004) Article DOI: 10.1016/j.bmcl.2004.09.077 BindingDB Entry DOI: 10.7270/Q2ZS2W0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50138599 (CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics Curated by ChEMBL | Assay Description Inhibition of cytochrome P450 3A4 of isolated guinea pig heart | Bioorg Med Chem Lett 14: 549-52 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50138599 (CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics Curated by ChEMBL | Assay Description Inhibition of cytochrome P450 2C9 of isolated guinea pig heart | Bioorg Med Chem Lett 14: 549-52 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50138599 (CHEMBL154751 | N-(2,6-Dimethyl-phenyl)-2-{4-[(R)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CV Therapeutics Curated by ChEMBL | Assay Description Inhibition of cytochrome P450 1A2 of isolated guinea pig heart | Bioorg Med Chem Lett 14: 549-52 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HD4 | |||||||||||
More data for this Ligand-Target Pair |