BindingDB PrimarySearch

Found 5 hits of ic50 for monomerid = 50148478
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peregrin (Homo sapiens (Human))	BDBM50148478 (CHEMBL3769965 \| US10702504, Compound A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of BRPF1B (unknown origin) by Alpha Screen assay				J Med Chem 59: 1642-7 (2016) Article DOI: 10.1021/acs.jmedchem.5b00458 BindingDB Entry DOI: 10.7270/Q2JS9S9G
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription intermediary factor 1-alpha (Homo sapiens (Human))	BDBM50148478 (CHEMBL3769965 \| US10702504, Compound A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by Alpha Scr...				J Med Chem 59: 1642-7 (2016) Article DOI: 10.1021/acs.jmedchem.5b00458 BindingDB Entry DOI: 10.7270/Q2JS9S9G
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcription intermediary factor 1-alpha (Homo sapiens (Human))	BDBM50148478 (CHEMBL3769965 \| US10702504, Compound A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC. US Patent					Assay Description The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...				US Patent US10702504 (2020) BindingDB Entry DOI: 10.7270/Q22B921C
DANA-FARBER CANCER INSTITUTE, INC. US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 1 (Homo sapiens (Human))	BDBM50148478 (CHEMBL3769965 \| US10702504, Compound A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assay				J Med Chem 59: 1642-7 (2016) Article DOI: 10.1021/acs.jmedchem.5b00458 BindingDB Entry DOI: 10.7270/Q2JS9S9G
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Bromodomain and PHD finger-containing protein 3 (Homo sapiens (Human))	BDBM50148478 (CHEMBL3769965 \| US10702504, Compound A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of BRPF3 (unknown origin) by Alpha Screen assay				J Med Chem 59: 1642-7 (2016) Article DOI: 10.1021/acs.jmedchem.5b00458 BindingDB Entry DOI: 10.7270/Q2JS9S9G
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair