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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50163368   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-sensitive inward rectifier potassium channel 1


(Rattus norvegicus (Rat))		BDBM50163368
PNG
(CHEMBL3794427)
Show SMILES FC1(CCc2ccc3C(=O)OCc3c2)CCN(CC1)C(=O)Cc1ccc(cc1)-n1cnnn1
Show InChI InChI=1S/C24H24FN5O3/c25-24(8-7-18-3-6-21-19(13-18)15-33-23(21)32)9-11-29(12-10-24)22(31)14-17-1-4-20(5-2-17)30-16-26-27-28-30/h1-6,13,16H,7-12,14-15H2
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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n/an/a 73n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assay

Bioorg Med Chem Lett 26: 2339-43 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.035
BindingDB Entry DOI: 10.7270/Q2668G3Q
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50163368
PNG
(CHEMBL3794427)
Show SMILES FC1(CCc2ccc3C(=O)OCc3c2)CCN(CC1)C(=O)Cc1ccc(cc1)-n1cnnn1
Show InChI InChI=1S/C24H24FN5O3/c25-24(8-7-18-3-6-21-19(13-18)15-33-23(21)32)9-11-29(12-10-24)22(31)14-17-1-4-20(5-2-17)30-16-26-27-28-30/h1-6,13,16H,7-12,14-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [35S]-MK499 from human ERG expressed in HEK293 cells

Bioorg Med Chem Lett 26: 2339-43 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.035
BindingDB Entry DOI: 10.7270/Q2668G3Q
More data for this
Ligand-Target Pair