BindingDB PrimarySearch

Found 9 hits of ic50 for monomerid = 50181153
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Curated by ChEMBL					Assay Description Inhibitory concentration against DOXP reductoisomerase				J Med Chem 48: 3547-63 (2005) Article DOI: 10.1021/jm0491501 BindingDB Entry DOI: 10.7270/Q2VH5Q21
Philipps University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DXR				ACS Med Chem Lett 2: 165-170 (2011) Article DOI: 10.1021/ml100243r BindingDB Entry DOI: 10.7270/Q2XD12NV
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductase				Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (docked)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Ghent University Curated by ChEMBL					Assay Description Inhibition of recombinant Escherichia coli DXR				Bioorg Med Chem Lett 16: 1888-91 (2006) Article DOI: 10.1016/j.bmcl.2005.12.082 BindingDB Entry DOI: 10.7270/Q2FJ2GB6
Ghent University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Ghent University Curated by ChEMBL					Assay Description Inhibition of recombinant Escherichia coli DXR				J Med Chem 49: 2656-60 (2006) Article DOI: 10.1021/jm051177c BindingDB Entry DOI: 10.7270/Q22F7N24
Ghent University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Mycobacterium tuberculosis)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis DXR assessed as reduction of 1-deoxy-D-xylulose 5-phosphate into 2-C-methyl-D-erythritol-4-phosphate measure...				Bioorg Med Chem Lett 21: 5403-7 (2011) Article DOI: 10.1016/j.bmcl.2011.07.005 BindingDB Entry DOI: 10.7270/Q290246H
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Mycobacterium tuberculosis)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen.				Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg/CNRS Curated by ChEMBL					Assay Description Inhibition of Mycobacterium smegmatis DSM 43756 ATCC 19420 N-terminal his-tagged DXR expressed in XL1-blue Escherichia coli using NADPH and DXP as su...				Eur J Med Chem 51: 277-85 (2012) Article DOI: 10.1016/j.ejmech.2012.02.031 BindingDB Entry DOI: 10.7270/Q2474BWK
Universit£ de Strasbourg/CNRS Curated by ChEMBL					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Mycobacterium tuberculosis)	BDBM50181153 (3-(N-hydroxyacetamido)propylphosphonic acid \| 3-(N...) Show SMILES CC(=O)N(O)CCCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis Dxr				Bioorg Med Chem Lett 24: 649-53 (2014) Article DOI: 10.1016/j.bmcl.2013.11.067 BindingDB Entry DOI: 10.7270/Q24Q7WGS
George Washington University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)