Found 6 hits of ic50 for monomerid = 50183063 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Heme oxygenase 1
(Rattus norvegicus (rat)) | BDBM50183063
((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)Show SMILES C[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1 Show InChI InChI=1S/C16H19ClN2O2/c1-13-10-20-16(21-13,11-19-9-8-18-12-19)7-6-14-2-4-15(17)5-3-14/h2-5,8-9,12-13H,6-7,10-11H2,1H3/t13-,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University
Curated by ChEMBL
| Assay Description
Inhibition of Sprague-Dawley rat spleen HO1 |
J Med Chem 49: 4437-41 (2006)
Article DOI: 10.1021/jm0511435
BindingDB Entry DOI: 10.7270/Q2GH9JR1 |
More data for this
Ligand-Target Pair | 
3D Structure (docked) |
Heme oxygenase 1
(Homo sapiens (Human)) | BDBM50183063
((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)Show SMILES C[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1 Show InChI InChI=1S/C16H19ClN2O2/c1-13-10-20-16(21-13,11-19-9-8-18-12-19)7-6-14-2-4-15(17)5-3-14/h2-5,8-9,12-13H,6-7,10-11H2,1H3/t13-,16-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University
Curated by ChEMBL
| Assay Description
Inhibition of human spleen HO1 |
J Med Chem 49: 4437-41 (2006)
Article DOI: 10.1021/jm0511435
BindingDB Entry DOI: 10.7270/Q2GH9JR1 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2E1
(Rattus norvegicus (rat)) | BDBM50183063
((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)Show SMILES C[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1 Show InChI InChI=1S/C16H19ClN2O2/c1-13-10-20-16(21-13,11-19-9-8-18-12-19)7-6-14-2-4-15(17)5-3-14/h2-5,8-9,12-13H,6-7,10-11H2,1H3/t13-,16-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University
Curated by ChEMBL
| Assay Description
Inhibition of rat liver CYP2E1 |
J Med Chem 49: 4437-41 (2006)
Article DOI: 10.1021/jm0511435
BindingDB Entry DOI: 10.7270/Q2GH9JR1 |
More data for this
Ligand-Target Pair | |
Heme oxygenase 2
(Rattus norvegicus (rat)) | BDBM50183063
((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)Show SMILES C[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1 Show InChI InChI=1S/C16H19ClN2O2/c1-13-10-20-16(21-13,11-19-9-8-18-12-19)7-6-14-2-4-15(17)5-3-14/h2-5,8-9,12-13H,6-7,10-11H2,1H3/t13-,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University
Curated by ChEMBL
| Assay Description
Inhibition of Sprague-Dawley rat brain HO2 |
J Med Chem 49: 4437-41 (2006)
Article DOI: 10.1021/jm0511435
BindingDB Entry DOI: 10.7270/Q2GH9JR1 |
More data for this
Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50183063
((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)Show SMILES C[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1 Show InChI InChI=1S/C16H19ClN2O2/c1-13-10-20-16(21-13,11-19-9-8-18-12-19)7-6-14-2-4-15(17)5-3-14/h2-5,8-9,12-13H,6-7,10-11H2,1H3/t13-,16-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.62E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University
Curated by ChEMBL
| Assay Description
Inhibition of rat brain nNOS |
J Med Chem 49: 4437-41 (2006)
Article DOI: 10.1021/jm0511435
BindingDB Entry DOI: 10.7270/Q2GH9JR1 |
More data for this
Ligand-Target Pair | |
Heme oxygenase 2
(Rattus norvegicus (rat)) | BDBM50183063
((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)Show SMILES C[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1 Show InChI InChI=1S/C16H19ClN2O2/c1-13-10-20-16(21-13,11-19-9-8-18-12-19)7-6-14-2-4-15(17)5-3-14/h2-5,8-9,12-13H,6-7,10-11H2,1H3/t13-,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.32E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Queen's University
Curated by ChEMBL
| Assay Description
Inhibition of rat liver HO2 |
J Med Chem 49: 4437-41 (2006)
Article DOI: 10.1021/jm0511435
BindingDB Entry DOI: 10.7270/Q2GH9JR1 |
More data for this
Ligand-Target Pair | |
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