Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM50184049 (3-(6-(2-(3,4,5-trimethoxyphenylamino)-7H-pyrrolo[2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of FAK (31-686) (unknown origin) using 32P-ATP after 2 hrs incubation measured by scintillation counting | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00338 BindingDB Entry DOI: 10.7270/Q2DJ5K8C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM50184049 (3-(6-(2-(3,4,5-trimethoxyphenylamino)-7H-pyrrolo[2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL | Assay Description Inhibition of FAK | Bioorg Med Chem Lett 16: 2689-92 (2006) Article DOI: 10.1016/j.bmcl.2006.02.032 BindingDB Entry DOI: 10.7270/Q2NK3DN0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |