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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50193237   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vitamin K-dependent protein C


(Homo sapiens (Human))
BDBM50193237
PNG
(CHEMBL379430 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Show SMILES C[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N
Show InChI InChI=1S/C23H27N5O4/c1-14(26-13-19(29)30)21(31)28-23(10-17-4-2-3-5-18(17)11-23)22(32)27-12-15-6-8-16(9-7-15)20(24)25/h2-9,14,26H,10-13H2,1H3,(H3,24,25)(H,27,32)(H,28,31)(H,29,30)/t14-/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 9.08E+3n/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Inhibition of human aPC


J Med Chem 49: 5047-50 (2006)


Article DOI: 10.1021/jm0606950
BindingDB Entry DOI: 10.7270/Q2H994VN
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50193237
PNG
(CHEMBL379430 | {(R)-1-[2-(4-carbamimidoyl-benzylca...)
Show SMILES C[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N
Show InChI InChI=1S/C23H27N5O4/c1-14(26-13-19(29)30)21(31)28-23(10-17-4-2-3-5-18(17)11-23)22(32)27-12-15-6-8-16(9-7-15)20(24)25/h2-9,14,26H,10-13H2,1H3,(H3,24,25)(H,27,32)(H,28,31)(H,29,30)/t14-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Inhibition of human thrombin activity


J Med Chem 49: 5047-50 (2006)


Article DOI: 10.1021/jm0606950
BindingDB Entry DOI: 10.7270/Q2H994VN
More data for this
Ligand-Target Pair