BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50202479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))		BDBM50202479
PNG
(CHEBI:69714 | Euphorbiaproliferin C)
Show SMILES [H][C@]12[C@@H](OC(=O)C(C)C)[C@@H](C)C[C@]1(OC(C)=O)[C@@H](OC(C)=O)[C@]1(C)OC[C@@]3([C@@H]2OC(C)=O)C(=O)C=C[C@@H]([C@@]13[H])C(C)(C)OC(C)=O |r,c:36|
Show InChI InChI=1S/C32H44O12/c1-15(2)27(38)42-24-16(3)13-32(44-20(7)36)23(24)26(40-17(4)33)31-14-39-30(10,28(32)41-18(5)34)25(31)21(11-12-22(31)37)29(8,9)43-19(6)35/h11-12,15-16,21,23-26,28H,13-14H2,1-10H3/t16-,21-,23+,24-,25-,26+,28-,30+,31+,32+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



Rytmion Ltd.

Curated by ChEMBL


Assay Description
Inhibition of GTPgammaS-induced activation of GIRK1/4 (unknown origin) expressed in HEK293 cells assessed as decrease in channel current after 2 mins...

J Nat Prod 79: 1990-2004 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00260
BindingDB Entry DOI: 10.7270/Q2CC12NJ
More data for this
Ligand-Target Pair