Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse)) | BDBM50207795 (CHEMBL246952 | adamantan-1-yl-(3,4-dihydro-2H-quin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 481 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assay | Bioorg Med Chem Lett 17: 2838-43 (2007) Article DOI: 10.1016/j.bmcl.2007.02.057 BindingDB Entry DOI: 10.7270/Q2CJ8D5S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50207795 (CHEMBL246952 | adamantan-1-yl-(3,4-dihydro-2H-quin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Curated by ChEMBL | Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assay | Bioorg Med Chem Lett 17: 2838-43 (2007) Article DOI: 10.1016/j.bmcl.2007.02.057 BindingDB Entry DOI: 10.7270/Q2CJ8D5S | |||||||||||
More data for this Ligand-Target Pair |