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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50213667   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50213667
PNG
((S)-2-(2-chlorophenyl)-1-(2-(3,5-dimethylphenyl)-3...)
Show SMILES C[C@H](CNCCc1ccncc1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1Cl
Show InChI InChI=1S/C33H37ClN4O/c1-22-16-23(2)18-27(17-22)33-32(24(3)20-36-14-10-25-8-12-35-13-9-25)28-21-38(15-11-30(28)37-33)31(39)19-26-6-4-5-7-29(26)34/h4-9,12-13,16-18,24,36-37H,10-11,14-15,19-21H2,1-3H3/t24-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 267n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]-inositol phosphate hydrolysis


Bioorg Med Chem Lett 17: 3845-50 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.009
BindingDB Entry DOI: 10.7270/Q2JD4WHQ
More data for this
Ligand-Target Pair