Found 3 hits of ic50 for monomerid = 50219413 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D
(Homo sapiens (Human)) | BDBM50219413
(CHEMBL81226)Show SMILES CCOC(=O)C(=O)N1Cc2cc(OC)ccc2C(Cc2c(Cl)cncc2Cl)=N1 |c:28| Show InChI InChI=1S/C19H17Cl2N3O4/c1-3-28-19(26)18(25)24-10-11-6-12(27-2)4-5-13(11)17(23-24)7-14-15(20)8-22-9-16(14)21/h4-6,8-9H,3,7,10H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D
(Homo sapiens (Human)) | BDBM50219413
(CHEMBL81226)Show SMILES CCOC(=O)C(=O)N1Cc2cc(OC)ccc2C(Cc2c(Cl)cncc2Cl)=N1 |c:28| Show InChI InChI=1S/C19H17Cl2N3O4/c1-3-28-19(26)18(25)24-10-11-6-12(27-2)4-5-13(11)17(23-24)7-14-15(20)8-22-9-16(14)21/h4-6,8-9H,3,7,10H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
Zambon Group
Curated by ChEMBL
| Assay Description
Inhibition of human neutrophil phosphodiesterase type IV (PDE4) |
Bioorg Med Chem Lett 12: 5-8 (2002)
BindingDB Entry DOI: 10.7270/Q2SB47Z5 |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D
(Homo sapiens (Human)) | BDBM50219413
(CHEMBL81226)Show SMILES CCOC(=O)C(=O)N1Cc2cc(OC)ccc2C(Cc2c(Cl)cncc2Cl)=N1 |c:28| Show InChI InChI=1S/C19H17Cl2N3O4/c1-3-28-19(26)18(25)24-10-11-6-12(27-2)4-5-13(11)17(23-24)7-14-15(20)8-22-9-16(14)21/h4-6,8-9H,3,7,10H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against phosphodiesterase 4. |
Bioorg Med Chem Lett 13: 2473-9 (2003)
BindingDB Entry DOI: 10.7270/Q24F1SXB |
More data for this
Ligand-Target Pair | |
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