Found 4 hits of ic50 for monomerid = 50228246 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B
(Homo sapiens (Human)) | BDBM50228246
(Indolidan)Show SMILES CC1(C)C(=O)Nc2ccc(cc12)C1=NNC(=O)CC1 |t:14| Show InChI InChI=1S/C14H15N3O2/c1-14(2)9-7-8(3-4-11(9)15-13(14)19)10-5-6-12(18)17-16-10/h3-4,7H,5-6H2,1-2H3,(H,15,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of PDE 3 (phosphodiesterase III) from guinea pig ventricle |
J Med Chem 36: 1387-92 (1993)
BindingDB Entry DOI: 10.7270/Q2JW8FHP |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Mus musculus (mouse)) | BDBM50228246
(Indolidan)Show SMILES CC1(C)C(=O)Nc2ccc(cc12)C1=NNC(=O)CC1 |t:14| Show InChI InChI=1S/C14H15N3O2/c1-14(2)9-7-8(3-4-11(9)15-13(14)19)10-5-6-12(18)17-16-10/h3-4,7H,5-6H2,1-2H3,(H,15,19)(H,17,18) | MMDB
KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D
(Homo sapiens (Human)) | BDBM50228246
(Indolidan)Show SMILES CC1(C)C(=O)Nc2ccc(cc12)C1=NNC(=O)CC1 |t:14| Show InChI InChI=1S/C14H15N3O2/c1-14(2)9-7-8(3-4-11(9)15-13(14)19)10-5-6-12(18)17-16-10/h3-4,7H,5-6H2,1-2H3,(H,15,19)(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of sarcoplasmic reticulum Phosphodiesterase 4 |
J Med Chem 32: 1476-80 (1989)
BindingDB Entry DOI: 10.7270/Q2P271B2 |
More data for this Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B
(Homo sapiens (Human)) | BDBM50228246
(Indolidan)Show SMILES CC1(C)C(=O)Nc2ccc(cc12)C1=NNC(=O)CC1 |t:14| Show InChI InChI=1S/C14H15N3O2/c1-14(2)9-7-8(3-4-11(9)15-13(14)19)10-5-6-12(18)17-16-10/h3-4,7H,5-6H2,1-2H3,(H,15,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of cardiac phosphodiesterase-3 isolated from canine heart. |
J Med Chem 33: 380-6 (1990)
BindingDB Entry DOI: 10.7270/Q241708F |
More data for this Ligand-Target Pair | |