Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50231039 (CHEMBL252657 | sodium; (3R,5R)-7-[2,3-bis-(4-fluor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of rat microsomal HMGCoA reductase | Bioorg Med Chem Lett 18: 1151-6 (2008) Article DOI: 10.1016/j.bmcl.2007.11.124 BindingDB Entry DOI: 10.7270/Q2TQ6191 | |||||||||||
More data for this Ligand-Target Pair |