new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50231774   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type X alpha subunit


(Mus musculus)
BDBM50231774
PNG
(5-(4-chlorophenyl)-N-cyano-N'-(3-methylphenyl)fura...)
Show SMILES Cc1cccc(c1)N=C(NC#N)c1ccc(o1)-c1ccc(Cl)cc1 |w:7.7|
Show InChI InChI=1S/C19H14ClN3O/c1-13-3-2-4-16(11-13)23-19(22-12-21)18-10-9-17(24-18)14-5-7-15(20)8-6-14/h2-11H,1H3,(H,22,23)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assay


J Med Chem 51: 407-16 (2008)


Article DOI: 10.1021/jm070637u
BindingDB Entry DOI: 10.7270/Q2KK9CN7
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50231774
PNG
(5-(4-chlorophenyl)-N-cyano-N'-(3-methylphenyl)fura...)
Show SMILES Cc1cccc(c1)N=C(NC#N)c1ccc(o1)-c1ccc(Cl)cc1 |w:7.7|
Show InChI InChI=1S/C19H14ClN3O/c1-13-3-2-4-16(11-13)23-19(22-12-21)18-10-9-17(24-18)14-5-7-15(20)8-6-14/h2-11H,1H3,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of hERG potassium channel expressed in CHO cells by isotope efflux assay


J Med Chem 51: 407-16 (2008)


Article DOI: 10.1021/jm070637u
BindingDB Entry DOI: 10.7270/Q2KK9CN7
More data for this
Ligand-Target Pair