BindingDB PrimarySearch

Found 5 hits of ic50 for monomerid = 50252236
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50252236 ((S)-N-(1-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethyla...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				Bioorg Med Chem Lett 18: 4075-80 (2008) Article DOI: 10.1016/j.bmcl.2008.05.104 BindingDB Entry DOI: 10.7270/Q2V40V03
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50252236 ((S)-N-(1-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethyla...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant IGF-1R tyrosine kinase expressed in baculovirus system assessed as [33gamma]ATP phosphorylation of poly(Glu/Tyr) subs...				Bioorg Med Chem Lett 20: 1744-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.087 BindingDB Entry DOI: 10.7270/Q2MW2H95
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50252236 ((S)-N-(1-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethyla...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of IGF1R (unknown origin)				Bioorg Med Chem Lett 18: 4075-80 (2008) Article DOI: 10.1016/j.bmcl.2008.05.104 BindingDB Entry DOI: 10.7270/Q2V40V03
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Mus musculus)	BDBM50252236 ((S)-N-(1-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethyla...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of IGF1R in mouse SAL cells assessed as thymidine incorporation				Bioorg Med Chem Lett 18: 4075-80 (2008) Article DOI: 10.1016/j.bmcl.2008.05.104 BindingDB Entry DOI: 10.7270/Q2V40V03
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50252236 ((S)-N-(1-(2-(4-(2-(3-chlorophenyl)-2-hydroxyethyla...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of CYP3A4 after 20 mins by BFC fluorescence assay				Bioorg Med Chem Lett 20: 1744-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.087 BindingDB Entry DOI: 10.7270/Q2MW2H95
Bristol-Myers Squibb Co. Curated by ChEMBL					More data for this Ligand-Target Pair