Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase I isoform delta (Homo sapiens (Human)) | BDBM50263829 (3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eberhard-Karls-University Curated by ChEMBL | Assay Description Inhibition of human CK1delta | J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform alpha (Homo sapiens (Human)) | BDBM50263829 (3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter | Eur J Med Chem 56: 30-38 (2012) Article DOI: 10.1016/j.ejmech.2012.08.007 BindingDB Entry DOI: 10.7270/Q2FJ2J2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform delta (Homo sapiens (Human)) | BDBM50263829 (3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Inhibition of human CK1delta using casein as substrate in presence of [gamma-32P]-ATP | Nat Rev Drug Discov 16: 424-440 (2017) Article DOI: 10.1038/nrd.2016.266 BindingDB Entry DOI: 10.7270/Q2125VNC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform epsilon (Homo sapiens (Human)) | BDBM50263829 (3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Inhibition of human CK1epsilon using casein as substrate in presence of [gamma-32P]-ATP | Nat Rev Drug Discov 16: 424-440 (2017) Article DOI: 10.1038/nrd.2016.266 BindingDB Entry DOI: 10.7270/Q2125VNC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform delta (Homo sapiens (Human)) | BDBM50263829 (3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt Curated by ChEMBL | Assay Description Inhibition of human CK1delta expressed in simian genome expressing mouse 3T3 cells | Bioorg Med Chem Lett 20: 2958-63 (2010) Article DOI: 10.1016/j.bmcl.2010.02.110 BindingDB Entry DOI: 10.7270/Q2Z89CKN | |||||||||||
More data for this Ligand-Target Pair |